PD linked mutation may cause neurodegeneration via different mechanism.
<h3>What is Novel Parkinson's disease linked mutation ?</h3>
A novel mutation in the α-Synuclein (α-Syn) gene "G51D" was recently identified in two familial cases exhibiting features of Parkinson's disease (PD) and multiple system atrophy (MSA)
- the G51D mutation significantly attenuates α-Syn aggregation in vitro.
- it disrupts local helix formation in the presence of SDS, decreases binding to lipid vesicles C-terminal to the site of mutation and severely inhibits helical folding in the presence of acidic vesicles.
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Answer:
The nucleus
Explanation:
Eukaryote ribosomes are produced and assembled in the nucleolus. Ribosomal proteins enter the nucleolus and combine with the four rRNA strands to create the two ribosomal subunits
Answer:
Food chains show a single path of energy in an ecosystem, and food webs show overlapping pathways of energy in that ecosystem.
Explanation:
Unlike food chains, food webs show more detailed information about the different animals in an ecosystem and show multiple energy transfers to different animals from the same sources.
By looking at these examples, you will notice a dramatic difference in detail:
In human body temperature is kept fairly constant by automatic responses controlled by hypothalamus. It secrete neurohormone , called as hypothalamic releasing hormone which stimulate and secrete pituitary hormones. Hypothalamus is responsible for the control of body temperature.