Question

Parathyroid hormone (PTH) is secreted in response to a drop in calcium levels in the blood. The secretion of PTH is regulated by a negative feedback mechanism. What can you expect to happen to calcium blood levels as increased amounts of PTH are secreted? Why

Answer 1

Answer:

An excess of calcium in the blood produces a disorder called primary hyperparathyroidism.

Explanation:

Calcium is a mineral found mostly in bones, where it builds up and keeps them strong. There is also a small amount of calcium in the muscles and blood cells, where it performs several important functions. When the calcium level is low, the parathyroid glands (four small glands located in the neck) produce a hormone called parathyroid hormone. Its main metabolic function is to maintain the levels of ionic calcium in the blood and phosphate within normal limits. Hyperparathyroidism is a disorder that lies in the parathyroid glands themselves, in such a way that an excessive and autonomous secretion of parathyroid hormone is produced from them, which changes the metabolism of calcium producing hypercalcemia and bone structural alterations. It is usually caused by the presence of autonomous adenomas, which affect a single gland. Excess calcium in the blood can lead to osteoporosis (weakening of the bones) and kidney stones.