Blood clots will do this. Cutting off blood flow while also increasing blood pressure. Also, if the viscosity (thickness of the blood) is thick which will slow down the flow and cause the body to use more effort to pump blood.
They play an important role in the control system by sensing defects that occur during essential processes such as DNA replication or chromosome segregation, and inducing a cell cycle arrest in response until the defects are repaired.
The order of the planets from closest to the Sun outwards is; Mercury, Venus, Earth, Mars, Jupiter, Saturn, Uranus and finally Neptune. The largest planet in the solar system is Jupiter, followed by Saturn, Uranus, Neptune, Earth, Venus, Mars with the smallest being Mercury.
