Question

A client is taking low-dose aspirin daily for her heart. the client is not receiving all the dosage of the aspirin that is being ingested because of:

Answer 1

Ans.

The first pass effect is defined as a phenomenon of metabolism of drug, in which drug concentration is greatly decreased before reaching the systemic circulation. It represents that fraction of drug lost, at the time of absorption of drug in gut.

Thus, the client is not receiving all the dosage of ingested drug (aspirin) because of the 'first pass effect.'