Question

A person with the genetic disorder Klinefelter's syndrome has an extra x-chromosome (genotype XXY). What can you predict is the most likely genetic mutation that results in Klinefelter's syndrome?

Answer 1

Answer:

The correct answer is non-disjunction at the time of meiosis.

Explanation:

A disorder, which takes place in males exhibiting an additional X-chromosome and is an outcome of an error in cell differentiation resulting in anomaly known as the Klinefelter's syndrome. Due to non-disjunction the egg or the sperm may acquire an additional X-chromosome. When these unusual cells take part in the genetic makeup of a person, then that individual most probably suffers from the condition termed as Klinefelter's syndrome.  

In the majority of the circumstances, the division of the cells takes place generally during the development of the sperm, and at the same time, there may be certain errors at the time of egg development. Generally, the condition is mostly seen in the offspring of women that conceive after the age of 35.