Answer: Europeans carried deadly (to the Native Americans) diseases
Explanation: When getting cured of a disease your body will have some type of immunity to the disease. If it is common from where you are then it wouldn't be too harmful. However, Native Americans getting new European diseases harmed them because this was new and they had no immunity. This made these diseases deadly to them.
The die is cast means an event has happened or a decision has been taken that cannot be changed. It is also a variation of a Latin phrase attributed by Suetonius to Julius Caesar on January 10, 49 BC, as he led his army across the Rubicon river in Northern Italy.
Today, the phrase crossing the Rubicon is an idiom that means to pass a point of no return.
Destroyed Europe--the ape is representing Germany and he has taken a lady (representing liberty). He is stepping onto the shores of America with Europe in the background destroyed.
This poster encourages support for US entry into World War I to protect the values of liberty in America. It suggests that Germany is made with power and will not stop with Europe but will continue to the US to destroy America as well.