Select ALL ways that acetyl-CoA can be used in a liver cell. Select ALL ways that acetyl-CoA can be used in a liver cell. Acetyl
-CoA can be converted to ketone bodies. Acetyl-CoA can enter the citric acid cycle for further oxidation. Acetyl-CoA can be converted to pyruvate and used to synthesize glucose. Acetyl-CoA can be used to synthesize fatty acids.
The following statements about acetyl-CoA functions in a liver cell are correct:
"Acetyl-CoA can enter the citric acid cycle for further oxidation."
"Acetyl-CoA can be used to synthesize fatty acids."
Explanation:
The first statement is incorrect. It is actually the ketone bodies that are converted to acetyl-CoA in the liver tissue, which can then be utilized in the citric acid cycle.
The second statement is correct. A series of chemical reactions converts acetyl-CoA, together with oxaloacetate, to yield a citrate molecule.
The third statement is incorrect. It is in fact the oxidation of pyruvate that produces acetyl-CoA, which is was glucose before that.
The fourth statement is correct. Those acetyl-CoA and aceacetoacetate molecules that are derived from amino acids can be used to synthesize fatty acids.
There are four fates for acetyl CoA in the human body. Here are all the fates of acetyl CoA:
Explanation:
1. Acetyl CoA in the mitochondria can be used in the electron transport chain to form CO₂ and water.
2. Acetyl CoA can synthesize ketonebodies which are oxidized for energy in the liver.
3. Acetyl CoA outside of the mitochondria and inside the cytosol can also be used to make fatty acids from glucose.
4. Acetyl CoA in the cytoplasm will also go on to synthesize cholesterol.
Altogether, the functions of acetyl CoA in the body is diverse and multi functional. The cells in other parts of the body do most of these functions but the ketone bodies formed in the liver creates a large amount of ketone bodies that are transported elsewhere.
