Partial or complete loss of hearing can be caused by damage to the; I, II, and III, that is, the axons of the neurons associated with each hair cell that carry information to the brain, hair cells in the cochlea and also the tympanic membrane. Hearing impairment, deafness or hearing loss is the inability to hear things, either totally or partially. This may be caused by injury or diseases that damages the parts responsible for hearing process.
The question is; would a drug that binds irreversibly to these receptors be an effective contraceptive in mammals?, the answer is;Yes; because if the receptors are blocked the sperms will not be able to penetrate the zonal pellucida of the egg. Contraceptives prevents pregnancy by interfering with the normal process of ovulation, fertilization, and implantation.
Answer: Yes
Explanation:
I’m not sure why it seems right tho
Paliperidone has low affinity
for lipid-rich environments compared from the parent compound risperidone. Due to
its hydrophilicity characteristic, paliperidone is capable of hydrogen bonding
with other molecules containing water and hydroxyl groups. Lipophilicity is a
determining factor for the rate and degree of metabolism of the drug in the
body and for crossing the blood–brain barrier (BBB).
Moreover, these differences are
implicated in synaptic plasticity and neuronal firing effects in the mechanism
of mitochondrial movement, protein expression, and phosphorylation of the drug.
Paliperidone as a mood stabilizer is an active metabolite of risperidone with antipsychotic effects used
for the treatment of schizophrenia and its associated disorders.
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