The statement 'polypeptides in the ER are usually larger than polypeptides synthesized from the same mRNA that have not entered the ER' is false.
The rough endoplasmic reticulum is the site where polypeptides enter so that protein formation can take place. Apart from protein formation, polypeptides are needed for various other metabolic functions by the ER.
Those polypeptides that are smaller in size can enter the endoplasmic reticulum because of the entering space and the small size of the endoplasmic reticulum. On the other hand, the polypeptides that are large, although being synthesized from the same mRNA, stay outside as they cannot enter the ER due to their large size.
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Answer:
Transcription, mRNA (processing, transport, localization and stability), translation.
Explanation:
- Transcription is regulated in two levels, though chromatin regulation (methylation and acetylation) to loose or increase histone's affinity to DNA and through cis and trans elements such as promoters, enhancers, and silencers (cis) to active/deactivate and RNA polymerase and transcription factors and co-factors (trans).
- mRNA can be regulated using poly-A tails or 5'-caps to shorten or give them more time before they degrade, it could also be spliced to eliminate introns.
- In the translation stage, the regulation occurs during the initiation through a scanning procedure that ensures the 40s ribosomal subunit bind correctly to the untranslated portion of RNA
Hope this information is useful to you!
Algae, Bacteria and Fungi
