many of the natives died from imported diseases, which interior the instantaneous sense weren't the Spaniards' fault (that they had no concept-about disease concept then and may't be held in charge for his or her lack of understanding). yet, wide-spread, the answer is, "Badly." The conquistadors were after gold and treasure. even as they were given right here in the time of that some Indians had some and knew the position to get more advantageous, they did now no longer hesitate to enslave them and lead them to paintings for his or her new masters.
West Virginia didn't approve of slavery (Virginia held the HQ for the Confederacy at Richmond, so they were for it) and the Virginians who disapproved of slavery broke off and became West Virginia.
The Romans were initially interested in expansion via Sicily (which at that time was a cultural melting pot), part of which lay under Carthaginian control. At the start of the first Punic War, Carthage was the dominant power of the Western Mediterranean, with an extensive maritime empire.