Simply put, a genetic mutation comes from a change in the DNA; this change can result from an extrachromosomal element, an alteration of the inherited nucleotide...
The basic building block of nucleic acids, such as DNA and RNA. It is an organic compound made up of nitrogenous, a sugar, and a phosphate group (http://www.biology-online.org/dictionary/Nucleotide)
A. the distribution of sand on an ocean floor
Solving problems with science means that to solve the problem the scientific method is used. This method includes observing, research, hypothesis , test and conclusion with a help of lot high level theory.
Without science there is not strict process to follow in order to resolve the problem end get to a solution.