I would believe the correct responses would be option 1,2,4.
D-low elevation and low relief
Calcium is a chemical element with symbol Ca and atomic number 20. Calcium is a soft gray Group 2 alkaline earth metal, fifth-most-abundant element by mass in the Earth's crust. The ion Ca2+ is also the fifth-most-abundant dissolved ion in seawater by both molarity and mass, after sodium, chloride, magnesium, and sulfate.[5] Free calcium metal is too reactive to occur in nature. Calcium is produced in supernova nucleosynthesis.
Answer: No
Explanation: It is beneficial if the animals that are disadvantageous doesn't reproduce so it doesn't discredit natural selection. The traits in which variation is occured are more suitable for organism to live and reproduce in the environment are preserved and are passed from generation to generation.
However, natural selection effects limited number of progeny.