I think the right answer would be intercultural
Columbus's voyage will start the Columbian Exchange. This was a an exchange of fruits, vegetables, plants, and animals. Natives became introduced to many things that were not native to the Americas. Natives will be taken and sold into slavery and almost completely wiped out due to European diseases.
I make little hits for them. Like, if one looks like a L then I add a name for it and memorize it as that.