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prohojiy [21]
3 years ago
14

Question 2 of 5

Health
1 answer:
denis-greek [22]3 years ago
6 0
15 percent under weight
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To infect T cells, M-tropic human immunodeficiency virus-1 (HIV-1) strains bind to the cell surface protein CCR5, which is norma
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In the case of HIV-1, this loss-of-function mutation has proven to be beneficial.

Explanation:

Loss-of-function mutations are those that result in a gene product that has less or no function compared to the unmutated gene. When the allele completely loses function, (null allele), it is called an amorphous mutation. Phenotypes associated with these mutations are usually recessive, except when the organism is haploid, or when the reduced dosage of the normal gene is not sufficient to produce a normal phenotype (this phenomenon is called haploinsufficiency).

As mentioned earlier, this type of mutation results in a defective gene, but the text shown in the above question shows an example of a beneficial loss-of-function mutation because this mutation provides resistance to HIV-1 infection.

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