Coal can't be created by the sun's energy.
Answer:
Around 70% of our immune system dwells in our digestive tract in the form of gut-associated lymphoid tissue (GALT). An important component of our immune system called plasma cells (which give rise to invader-defending antibodies) also reside within the GALT. Our gut is the major channel between the external environment and the internal systems of our body. It is exposed to plenty of germs and harmful invaders such as bacteria and viruses present in food particles on a daily basis. [1] These toxic agents are perceived by the immune system in the gut as being harmful to our body and attacked. That being said, our body does not reject everything we put into it. This process is known as tolerance. When our immune system rejects an otherwise harmless substance, we are labeled as being sensitive or allergic to that food/food ingredient.
Explanation:
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Answer:
survive in their environment
Explanation:
According to Darwin's theory of evolution, natural selection is the main mechanism. Darwin explains that organisms that have heritable traits that help them survive and reproduce, will be favorable by natural selection. Those favorable traits will enable organism to better adapt to their environment and to pass more genes on to the next generation (offspring).
Organisms adapt to their environment by changing their behavior, structural traits or physiology as a response to environmental change, so that they become well suited to it.
Mosunetuzumab is a T-cell reliant bispecific antibody that binds to CD3 and CD20 to trigger T-cell mediated B-cell death.
However, cytokine release syndrome, which has the potential to limit dose and efficacy, can result from powerful immune stimulation with T-cell focused treatments.
We created a novel mechanistic model of immune and antitumor responses to the T-cell bispecifics (mosunetuzumab and blinatumomab), taking into account the dynamics of B- and T-lymphocytes in circulation, lymphoid tissues, and tumors, in order to better understand the mechanisms underlying safety and efficacy as well as to explore safety mitigation strategies.
Using mosunetuzumab nonclinical and blinatumomab clinical data, the model was created and validated. The initial step-fractionated dose was projected to minimize systemic T-cell activation and cytokine release without impairing tumour response.
Simulations described the mechanisms underlying the observed cell and cytokine (IL6) dynamics. The Phase I clinical study for mosunetuzumab was changed to a step-fractionated treatment schedule as a result of these findings, allowing for the safer administration of greater dosages.
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The answer would be carbohydrate
Carbohydrate, mainly glucose, is the substrate that was used as the main source of energy production. The second energy source would be fat as it gives much more energy than carbohydrate and protein. Protein is used for making new body cells and repairing the damaged one.
