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In general, negative selection eliminates from the population very harmful changes to proteins that kill or stop reproduction. ... The authors also found a correlation between genes predicted to be under negative selection and genes implicated in certain hereditary diseases
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Answer:
What causes genetic variation?
Genetic variation can be caused by mutation (which can create entirely new alleles in a population), random mating, random fertilization, and recombination between homologous chromosomes during meiosis (which reshuffles alleles within an organism’s offspring).
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