Answer:
C. The substance does not directly harm tissues and is not a pathogen, but nevertheless triggers an inflammatory response.
Explanation:
When a person is allergic to a substance, his or her immune system recognizes a harmless substance, such as components in food, pollen, or dust, as a treat. As a consequence, it starts an immune response that leads to inflammation. The substance that starts the allergic reaction is called an allergen, and it is not a pathogen because it is not a real threat to the body since it does not infect cells. When the allergen enters the body, it binds to antibodies that are in contact with a special type of cell. These specific cells will release a substance known as histamine. Histamine will produce an inflammatory reaction affecting different tissues in our body. For example, it can make us sneeze, have a running nose, swelling parts of our body, have itchiness and redness, amongst others.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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The cells will make some sort of reaction, there's no doubt about it. But for a bass I believe that their cells will stay the same or shrink over time.
Bass are strong fish and they usually do well when there's a change in conditions made in the environment. But it depends on what this river has in it and if it leads to bigger opened waters.
If there's a shortage of food sources for the bass it'll have to adapt quickly or it'll die from the predators in the area. If there isn't any places the Bass can lay their eggs (reproduce) its population will die in that river.
There also competition. In that river it could have socked eye salmon in it or catfish even pikes. So the Bass cells would stay the same.
Hope this helps
Answer:
one is adopted and one is the child from the mother's previous marriage.
Explanation:
