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The correct answer is: A. A change in a cell's genetic material.
Mutations occur in DNA as a result of mistakes during the DNA replication (when repair mechanisms don’t fix it) or as the result of environmental factors (e.g. UV light). Mutations can have positive impact, by increasing the genetic variation or can have negative effect, causing the diseases or cancer.
The answer is 30 to 80 percent its in google
The Hardy-Weinberg equation is:

where p generally represents the frequency of the homozygous dominant population.
The q usually represents the frequency of the homozygous recessive population, and the 2pq term represents the frequency of the heterozygous population.