Opsonization is a term that refers to an immune process where particles such as bacteria are targeted for destruction by an immune cell known as a phagocyte . The process of opsonization is a means of identifying the invading particle to the phagocyte. Without the opsonization process the recognition and destruction of invading agents such as bacteria would be inefficient.
One of the most effective methods that can be used by researchers to avoid sampling bias is simple random sampling, in which samples are chosen strictly by chance. This provides equal odds for every member of the population to be chosen as a participant in the study at hand.