A vacuole is a membrane-bound organelle which is present in all plant and fungal cells and some protist, animal and bacterial cells. Vacuoles are essentially enclosed compartments which are filled with water containing inorganic and organic molecules including enzymes in solution, though in certain cases they may contain solids which have been engulfed.
It is the Fertile Crescent as the shapes of the river formed a rough crescent shape that was ripe for farming due to the easy irrigation and moist soil.