Answer:
The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.
Explanation:
Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.
Answer: Because according to the universal law of gravitation, the effect of the force of gravity decreases as the distance increases. The gravitation force is inversely proportional to the radius or the distance. So, the gravitational force exhibited by the Mars is not experienced by us due to the large distance.
Explanation:
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Answer: It is important that cells have a "control system" because without it cells would either divide too fast or cause tumors to grow (cancer), or divide too slow and not be able to perform their cellular functions which is why the cells are controlled.
