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Macrophages rid the body of worn-out cells and other debris.
The vacuole usually acts as storage for materials needed by the cell.
Looking at the food chain & relationships between organisms can give you a good idea of theoretical cause and effects.
For example:
Starfish are the natural predators of the mussel. If the starfish, that eat the mussels, were to be taken out of the picture: there would most likely be a higher population of mussels.