Answer:
Results
We systematically analyze and compare how different modelling methodologies can be used to describe translation. We define various statistically equivalent codon-based simulation algorithms and analyze the importance of the update rule in determining the steady state, an aspect often neglected. Then a novel probabilistic Boolean network (PBN) model is proposed for modelling translation, which enjoys an exact numerical solution. This solution matches those of numerical simulation from other methods and acts as a complementary tool to analytical approximations and simulations. The advantages and limitations of various codon-based models are compared, and illustrated by examples with real biological complexities such as slow codons, premature termination and feedback regulation. Our studies reveal that while different models gives broadly similiar trends in many cases, important differences also arise and can be clearly seen, in the dependence of the translation rate on different parameters. Furthermore, the update rule affects the steady state solution.
Conclusions
The codon-based models are based on different levels of abstraction. Our analysis suggests that a multiple model approach to understanding translation allows one to ascertain which aspects of the conclusions are robust with respect to the choice of modelling methodology, and when (and why) important differences may arise. This approach also allows for an optimal use of analysis tools, which is especially important when additional complexities or regulatory mechanisms are included. This approach can provide a robust platform for dissecting translation, and results in an improved predictive framework for applications in systems and synthetic biology.
hope it help friends
Answer:
reservoir.
Explanation:
The reservoir is a component of the biosphere that serves as a long term storage unit for the nutrients or the water. It is a storage space for fluids.
Smog from city areas is causing acid rain because the hazardous effects of acid rain are very noticeable in the environment and it says that fish were dying, trees were dying, and that the soil quality was suffering. Hope this helps
Answer:
Melting of glaciers and ice caps.
Explanation:
Global warming increases greenhouse gasses increasing heat, obvi. So that will cause the glaciers to melt. and with out glaciers there is no cold water without could water there is no convection current without convection current there are isnoway to move nutrients.
Answer:
<em>Exceptions to Mendel's principles:
</em>
Does exceptions mean that Mendel was "wrong"? The answer is "NO". It means that we know more today about diseases, genes, and heredity than compared to what he expalined 150 years ago. Here I have summerized the exceptions with examples:
<em>Incomplete dominance</em>: When an organism is heterozygous for a trait and both genes are expressed but not completely.
<em>Example</em><em>:</em> SnapDragon Flowers
<em>Codominance</em>: When 2 different alleles are present and both alleles are expressed.
<em>Example</em>: Black Feathers + Whites feathers --> Black and white speckled feathers
<em>Multiple alleles</em>: Three or more alternative forms of a gene (alleles) that can occupy the same locus.
Example: Bloodtype
<em>Polygenic traits</em>: more than one gene controls a particular phenotype
Example: human height, Hair color, weight, and eye, hair and skin color.