Question

Many proteins destined for the mitochondria are not folded properly prior to their destination. This ultimately means that the proteins will be inactive in the cytosol, while active in the mitochondrial matrix. What function do these proteins most likely serve? Why is it advantageous to have them be active in the mitochondrial matrix and not in the cytosol?

Answer 1

Answer: Mitochondrial proteins are generally involved in mitochondrial functioning and the functions they carry out

Explanation:

Mitochondrial proteins are synthesized in the cortisol by the ribosomes and are delivered as precursors to the mitochondria before folding and remodeling processes takes place which are carried out by the chaperones.

Mitochondrial proteins which resides in the matrix and the cristae are involved generally in mitochondria functions such as carrying the reactions in the electron transport chain among others.

The proteins which are already active at the cortisol may remain there, which is why it is advantageous for the proteins to be in their precursor state so that they will be properly targeted to the matrix to be synthesized and to function.