Pituitary dwarfism is caused by problems arising from the pituitary gland. The pituitary gland, also called the hypophysis, is a gland at the base of the brain that produces many different hormones. This gland is divided into the anterior (front) and posterior (back) halves. The anterior pituitary produces six hormones: growth hormone, adrenocorticotropin (corticotropin), thyroid stimulating hormone (thyrotropin), prolactin, follicle stimulating hormone, and lutenizing hormone. The posterior pituitary gland only produces two hormones: antidiuretic hormone (vasopressin) and oxytocin.
The growth process begins in the lower part of the forebrain in a small organ called the hypothalamus. The hypothalamus releases hormones that regulate the production of other hormones. When the hypothalamus releases growth hormone-releasing hormone (GHRH), the anterior pituitary is stimulated to release growth hormone (GH). Growth hormone then acts on the liver and other tissues and stimulates them to secrete insulin-like growth factor-1 (IGF-1). IGF-1 directly promotes the development of bone and muscle, causing bones to grow in length, and muscles to increase protein synthesis (make more protein).
Since growth is a complex phenomenon, it may be slowed down or stopped by abnormalities arising at any point in the process. Thus, dwarfism can result if there is a deficiency in any of these hormones, if there is a failure in the receptor cells receiving the hormonal stimuli, or if the target cells are unable to respond.
At its most basic, pituitary dwarfism results from decreased production of hormones by the anterior pituitary. When none of the hormones of the anterior pituitary are adequately produced, this is called panhypopituitarism. A common form of pituitary dwarfism is due to deficiencies in the production of growth hormone (GH). When less GH than normal is produced during childhood, an individual's arms, legs, and other structures continue to develop in normal proportions, but at a decreased rate.
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hopre i helped</span>
 
        
             
        
        
        
Long-term potentiation (LTP) is considered a cellular correlate of learning and memory. The presence of G protein-activated inwardly rectifying K(+) (GIRK) channels near excitatory synapses on dendritic spines suggests their possible involvement in synaptic plasticity. However, whether activity-dependent regulation of  channels affects excitatory synaptic plasticity is unknown. In a companion article we have reported activity-dependent regulation of GIRK channel density in cultured hippocampal neurons that requires activity oF receptors (NMDAR) and protein phosphatase-1 (PP1) and takes place within 15 min. In this study, we performed whole-cell recordings of cultured hippocampal neurons and found that NMDAR activation increases basal GIRK current and GIRK channel activation mediated by adenosine A(1) receptors, but not GABA(B) receptors. Given the similar involvement of NMDARs, adenosine  receptors, and PP1 in depotentiation of LTP caused by low-frequency stimulation that immediately follows LTP-inducing high-frequency stimulation, we wondered whether NMDAR-induced increase in GIRK channel surface density and current may contribute to the molecular mechanisms underlying this specific depotentiation. Remarkably, GIRK2 null mutation or GIRK channel blockade abolishes depotentiation of LTP, demonstrating that GIRK channels are critical for depotentiation, one form of excitatory synaptic plasticity.
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brainly.com/question/11985070
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Answer:
Un elemento químico es un tipo de materia constituida por átomos de la misma clase. En su forma más simple, posee un número determinado de protones en su núcleo haciéndolo pertenecer a una categoría única clasificada por su número atómico, aun cuando este pueda desplegar distintas masas atómicas.
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<span>The answer is (D) are k-selected.
Primates are the most K-selected among mammals. Individuals produce only a few whom
they invest a great amount of parental care. Reproductive strategies main goal
is to produce offspring and successfully rear them to adulthood.</span>
 
        
                    
             
        
        
        
The A antibodies will produce A antibodies and B antibodies will produce B antibodies