Our skin has receptors and muscles also have receptors which tells brain about how much tension is being exerted on it etc.
The role of the effector(s) that result in a short-term
cellular change in a changing the activation state of an enzyme going from
inact to act this happens for instance when activating an enzyme to increase
sugar metabolism while Long-term cellular changes are generally the result of
changes in DNA transcription, i.e. a protein can be made to begin cellular replication
by activating the cell cycle.
A.some of the genetic material is altered