Two genes, BRCA1, located on chromosome 17q21 (5,6), and BRCA2, located on 13q12-13 (7–9), have been shown to predispose to familial breast cancer.
The valves are responsible for preventing blood from flowing in the wrong direction, they are present in the veins, and the arteries don't need them because the aorta (biggest artery) pumps or in other words pushes it with such a force that no other force can change its direction, in the veins there is no structure present for pumping them as a result we have got valves so that they go in one direction...... the meaning of the word valve is to allow in one direction
