Answer:
Explanation:
A. Cancer cells are cancerous because they divide all the time. Normal cells stop dividing once there's enough of them but cancer cells divide when not required as well. Therefore, if Ras is mutated it will always be "on" which means it will activate the pathway which will lead to division of cells i.e. cells divide to multiply their numbers so more cells will be made. Normally, cells only multiply whne there's the growth factor present to activate the whole pathway, but since Ras is mutated it doesnt need the growth factor to activate the pathway, it automatically always activates the pathway even in absence of growth factor.
B. It is highly unlikely that the proposed drug will have a useful effect. This is because mutant Ras protein of this type behaves as though it is constantly "on". Ras acts downstream of the receptor, i.e. first you have the reception of growth factor in receptor, then the ras gets activated. However, the activating mutation makes its effect felt (Ras is activated no matter if there's a growth factor or not), which is why mutant Ras is always active and no longer dependent on the receptor for activation.
Therefore, blocking the ability of the receptor to dimerize and activate Ras will probably not have an effect on cells containing the mutant Ras protein as it does not inhibit the activity of mutated Ras protein.
(Check out the Ras/Ref/MEK/Erk pathway for better understanding of how significant role Ras protein plays in cell proliferation i.e. division)
<h2>Answer is option "c"</h2>
Explanation:
- Participant observation is a qualitative research method in which the researcher not only observes the research participants, but also actively engages in the activities of the research participants. This requires the researcher to become integrated into the participants' environment while also taking objective notes about what is going on. Most researchers who conduct participant observations take on the role that they are interested in studying.
- In Jill's case, she might enroll in an actual foreign language course, complete all assigned homework and classwork, and attend field trips just as any regular student enrolled in the class would. Jill would also have informal conversations with other students in the class and the teacher. Jill would keep a detailed record of all assignments and take detailed notes about what she observes and what happened during her encounters with her classmates and teachers. Jill would also keep notes about technology usage, classroom norms and expectations, and any other information that she finds useful.
- There are three important pieces of participant observation:
- Gaining entry into the location you wish to study.
- Establishing rapport with the research participants under investigation
- Making sure you spend enough time with the research participants in the environment to get a sufficient amount of data for your study.
- Hence, the right answer is option c "participant observation.
Answer:
See below
Explanation:
A) First of all, it must be considered that HIV has a RNA genome.
The reverse transcriptase is a viral enzyme able to convert a RNA molecule (in this case the RNA would be the viral genome) to DNA. This process is important for two reasons:
* The DNA molecule is more stable than RNA --> Therefore, there is a higher likely that the molecule wouldn't be degradated by the host.
* The viral genome made of DNA will be integrated into the host genome --> To do so, it requires to be DNA instead of RNA
B) The inibitor is able to target the Reverse Transcriptase --> So, the likehood of converting RNA to DNA is lower. In this case, the single RNA molecule is less stable than the DNA and the host can degradate it more easily.
C) In general, the viral will not survive the treatment and, hence, the patient will not suffer from the viral infection
Answer:
Adenosine triphosphate (ATP), energy-carrying molecule found in the cells of all living things. ATP captures chemical energy obtained from the breakdown of food molecules and releases it to fuel other cellular processes.
Explanation:
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Primase produces short sequences of RNA in order to provide a 3' reactive group for DNA polymerase to act on.