Cairo, since it is in the Nile Delta area, which is by definition not Nubia
The United States' total cotton output tripled between 1816 and 1826. Cotton continued to rise in value as the nation's primary export, and by 1836, would make up two-thirds of all American exports in terms of value.
I think it is political and corporate corruption
During the reign of Queen Elizabeth I, English seafarers were often involved in attacks on Spanish treasure ships and on trading settlements in the Americas. These were carried out with Queen Elizabeth I’s encouragement, in an attempt to weaken the power of Spain rather than capture the empire. England’s main concern was the threat of invasion by Spain, and after the defeat of the Spanish Armada in 1588, England could feel secure. Gradually England started to look to expand her own empire in North America, leaving South America to Spain and Portugal.