By injecting Mesenchymal Stem Cells with ability to express high amount of Akt or protein kinase B in myocardium, researchers witnessed restored cardiac function and inhibition of ventricular remodeling. The effect was seen after two weeks of administration of cells. The culture containing hypoxic Akt-MSCs (conditioned medium) inhibits apoptosis or cell death induced due to hypoxia. Also, it triggers in vitro contraction of cardiomyocytes, the cardiac cells specifically responsible for contraction function.
The desired functional improvement can occur in short time which is less than 72 hours, the reason for which was hypothesized as paracrine action of cells. Hypothesis was proved by upregulation of genes that code for factors responsible for above mentioned effects (apoptosis and contraction). The factors are FGF-2, VEGF, HGF etc.
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the answer is a or d and im leaning too a so i suggest getting a second opinion sorry i cant help much more than that.
Answer:
Explanation:
The last total eclipse in the U.S. was in 1979. And the last total solar eclipse that crossed the entire continental U.S. happened in 1918. But why? Why has it been 99 years, and why have the intervening partial and even total eclipses caught only parts of the country?
Not sure if its 100% correct but it's similar to that I think
Here's what he must do:
-- Run the experiment again, several times if possible. Combine or
analyze
the results of the several experimental runs in some statistically
valid way.
-- Run the simulation again, several times. Combine or analyze the results
of the several simulations in some statistically valid way.
-- Then, compare the analysis of several experimental runs with the analysis
of several simulations, in some statistically valid way, to decide whether they
<em>really</em> don't track.
-- If they do, then look for ways to tighten up the simulation so that maybe
they can track better.
-- If they don't, then he's back to <em>before</em> Square-1. He not only has to
deal with the question of whether or not his experiment is valid, but he
also has to consider the possibility that his simulation is trash and
doesn't actually model nature like he expected it to.
