If a species is said to be extinct, then that species is reduced to zero. There are none living in existence. The affects to other organisms of its extinction would depend on their value to the ecosystem. Regardless, extinction completely stops evolution of the species extinct.
In some cases, massive destruction of red blood cells caused death. This drug-induced hemolytic anemia was shown 30 years later to be caused by a deficiency of glucose 6-phosphate dehydrogenase, the enzyme catalyzing the first step in the oxidative branch of the pentose phosphate pathway.
in short terms, glucose 6-phosphate dehydrogenase
Sperm production is hormonally driven. Brain hormones govern sperm production and are precisely controlled. So I say yes