Religion was the main cause
I’m pretty sure the answer is A yes.. hope this helps! :)
A) Giuliano della Rovere
Pope Julius II was born Giuliano della Rovere. During his nine-year pontificate his military and diplomatic interventions averted a take-over by France of the Italian States. He also commissioned a series of highly influential art and architecture projects in Rome
A. West of the Mississippi River
This was accquired through the Louisiana Purchase.