The higher the GC content of a DNA, the higher the strength of the interchain interactions, and the higher the melting temperature.
DNA is Deoxyribonucleic Acid. It is the genetic material in maximum of the organisms. The DNA is a polymer made from nucleotides (sugar, nitrogenous bases and phosphate group). It is composed of two strands of phosphate and sugar backbone in an antiparallel direction. The nitrogenous bases present in DNA are Adenine (A), Thymine (T), Guanine (G) and Cytosine (C).
GC content refers to the total amount of Guanine and Cytosine present in the DNA. Since there exists a triple bond between G and C, more percentage of them provides strength to DNA. That is why high GC content denotes high melting temperature of DNA.
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