Answer:
b 
Explanation:
the mates will want a pretty mates , therefore b is correct 
 
        
             
        
        
        
Answer:
Constitutive activation is the alteration of a protein or signaling pathway such that it is functional or engaged even in the absence of an upstream activating event. For example, RasD is constitutively active because it cannot bind GAP and therefore remains in the GTP-bound, active state even when cells are not stimulated by growth factor to activate a receptor tyrosine kinase. 
Constitutively active Ras is cancer promoting because cells will proliferate in the absence of growth factors, and thus normal regulatory mechanisms for cell proliferation are bypassed.
(a) A mutation that resulted in Smad3 binding Smad4, entering the nucleus, and activating transcription independent of phosphorylation by the TGFβ receptor would render Smad3 constitutively active.
(b) A mutation that made MAPK active as a kinase and able to enter the nucleus without being phosphorylated by MEK would render MAPK constitutively active.
(c) A mutation that prevented NF-KB from binding to IK-B or that allowed NF-KB to enter the nucleus and regulate transcription even when bound to IK-B would render NF-KB constitutively active.
 
        
             
        
        
        
The structures allow the cell to perform specific functions.  
 
        
                    
             
        
        
        
Answer:
It should be D 
Explanation: Hope this helps 
 
        
             
        
        
        
It disconnects the brain's dopamine system.
Further explanation
Cocaine
Cocaine is a capably addictive stimulant medication. For a great many years, individuals in South America have bitten and ingested coca leaves which is source of cocaine, for their stimulant effects. In the mid-1900s, refined cocaine was the primary dynamic fixing in numerous tonics and elixirs created to treat a wide assortment of diseases and was even a fixing in the early plans of Coca-Cola. Prior to the advancement of manufactured specialists utilized cocaine for the relief of pain. However, examine has since demonstrated that cocaine is an effectively addictive substance that can change cerebrum structure and capacity whenever utilized over and over.
Functions of cocaine
It shows very quickly effect after a solitary portion and vanish inside a couple of minutes to 60 minutes. Limited quantities of cocaine for the most part make the person feel euphoric, enthusiastic, loquacious, rationally caution, and easily affected to sight, sound, and contact. The medication can likewise briefly diminish the requirement for sustenance and sleep. Some clients find that cocaine encourages them perform straightforward physical and scholarly assignments all the more rapidly, in spite of the fact that others experience the contrary impact.
Effect of cocaine on dopamine
Cocaine particles block the dopamine transporters which shut down the neuron's capacity to take-up the additional dopamine inside the synaptic parted. This outcomes in expanded degrees of the synapse dopamine present in the extracellular spaces among these neurons.
Answer details
Subject: Biology
Level: College
Key words
- Cocaine
- Functions of cocaine
- Effect of cocaine on dopamine
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