There were multiple cultures that existed in the west before settlers from Europe came in and took over their land, and some of the most advanced and most recognizable are:
- Mississippi culture; it was the most advanced culture in North America, located alongside the Mississippi River in the United States.
- Aztec culture; it was the most advanced and strongest culture in Central America, located in the southern half of Mexico, Belize and Guatemala.
- Inca culture; it was the most advanced culture in South America, it was spread out on mostly on the territories of Peru, Bolivia, and Ecuador.