A group of Chinese women with PCOS who were receiving treatment saw several metabolic and hormonal imbalances improve after taking BBR. The primary consequences may be connected to the modifications in body composition in obesity and dyslipidemia. For the evaluation of the possible beneficial metabolic effects of BBR in women with PCOS, additional controlled trials are required.
PCOS:
- Objective: Insulin resistance is a common metabolic and reproductive condition called polycystic ovarian syndrome (PCOS) (IR). A quinoline derivative alkaloid known as berberine (BBR) has been utilized as an insulin sensitizer and is isolated from Chinese medicinal herbs. There may be a therapeutic benefit for PCOS from BBR. The purpose of this study was to compare the effects of BBR and metformin (MET) on the metabolic characteristics of PCOS-affected women.
- Design and methods: Ninety nine PCOS and IR patients were randomly assigned to one of three therapy groups: BBR+ compound cyproterone acetate (CPA;
), MET
CPA
, and placebo
CPA
for
months. Before and after the treatment period, metabolic and hormonal measures as well as the clinical characteristics of the women were evaluated. - Results: Reduced waist circumference, waist-to-hip ratio (WHR;P<
), total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDLC; P<
), as well as increased levels of high-density lipoprotein cholesterol (HDLC) and sex hormone-binding globulin (SHBG; P<
) were all observed following treatment with BBR as compared to MET. Similarly, BBR treatment decreased WHR, fasting plasma glucose, fasting insulin, homeostasis model evaluation for IR, area under the insulin curve, TC, LDLC, and TG (P<
), while increasing HDLC and SHBG (P<
) as compared to placebo.
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So this my friend is a Contact Force. Anything that involves pushing, pulling, or creating friction is a contact force. So you will say it’s a contact force. Please Mark me brainliest
Supply oxygen to cells for cellular respiration.
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The scaly skin of a snake is homologous to skin of a lizard.
Homologous is a term used to describe a part of two different animals that come from a common ancestor. This makes the part will have a very similar structure.
Other similar terms would be analogous where the part of the animals will have similar functions but comes from a different ancestor, thus have a different structure.