Enzymes and substrates are often specific for one another. They have shapes that can be modified to fit into each other which allows them to bind together (induced fit).T<span>ogether, Enzymes and substrates undergo some transformations </span><span>as they interact. They interact by forming hydrogen bonds, covalent bonds and what is also called hydrophobic interactions.</span>
The enzyme returns to its original shape and state after the reaction but the substrate is often modified or changed completely into a new, different product.