The main objective of phase 3 trials is to verify the therapeutic action of a new substance in a large number of patients, essentially to determine the risk/benefit ratio. Before phase 3, the substance is not regarded as a drug, but after a positive phase 3 trial it becomes a drug.
Answer:
c. The abnormality is in the thyroid gland itself.
Explanation:
Primary hypothyroidism arises from a pathology in the thyroid gland itself and occurs when the thyroid gland is not able to perform one of its many physiology. Secondary hypothyroidism starts at the level of the pituitary gland and results from under secretion of TSH. TSH is needed to trigger the release of the T3 and T4 stored in the thyroid gland. Tertiary hypothyroidism is caused by a decrease level of the TRH from the hypothalamus. This reduced level, in turn, reduces TSH and thyroid hormone levels in the blood, hence in the body and the patient suffer the symptoms.
Answer:
A word or phrase naming an attribute, added to or grammatically related to a noun to modify or describe it.
Explanation:
Examples are: beautiful, pretty, heavy.
Any descriptive words are adjectives.
Example Sentence: That is a thick noodle.
Thick is the adjective because it is adding description to the noun, which is noodle.
Hope this helps! Feel free to ask questions!
Answer:
Average temperature of water is -12°C (10°F)
Explanation:
Which water tho?