Answer;
-Large polar molecule are list likely to cross the phospholipid bilayer.
Explanation;
-A large polar molecule would be the least likely to passively diffuse through a plasma membrane without the help of a transport protein. Both its size and the hydrophobic interior of the membrane would restrict it.
-Only small uncharged molecules can diffuse freely through phospholipid bilayers. Small nonpolar molecules, such as O2 and CO2, are soluble in the lipid bilayer and therefore can readily cross cell membranes.
-Ions and large polar molecules cannot pass through the lipid bilayer. But more specifically, whether a molecule can pass through the membrane depends on its size and its electrical nature.
Missense mutations.
Hope this helps!
We see that this is a region near the continents, so it is probable that there is the boundary of a tectonic plates around there. Since there are islands there, it is quite probable that there is a subduction zone near them which means that the oceanic crust is going below the continental one and the continental is slowly elevated. This also shows that the boundary is convergent, since transform boundaries do not lead to elevation. Near convergent boundaries, there are frequently volcanoes and shallow earthquakes. Finally, the climate near Alaska is cold and this does not depend on whether islands are near a boundary or not. So, 2 4 and 5 are correct.
