Answer:
All of these choices are correct.
Explanation:
Cell cycle is the process of growth and division of cell. It comprises of interphase and mitosis. In interphase the cell grows, replicates its genomic content and prepares itself for division. In mitosis the division occurs.
Cell cycle is controlled by a group of kinases called as Cyclin dependent Kinases (CDKs). They act by phosphorylating their substrates. They are of various types like Cdk1, Cdk2, Cdk4 etc. They become active when they bind to a regulatory protein called cyclin. They are also of various types like Cyclin A, Cyclin B, Cyclin C etc. Level of cyclin and corresponding CDK increases and decreases according to the stage of cell cycle. For example in S phase of cell cycle concentration of cyclin A and E shoots up. CDK2 is able to bind to these cyclin molecules and hence it becomes active.
Cell cycle has major checkpoints where the condition of cell is analysed before it proceeds to the next stage of cycle. If any abnormality is detected, repair mechanism is activated or the cell is killed. Checkpoints do not allow cell cycle to proceed in damaged cells.
p53 is a tumor suppressor protein which can halt cell cycle when it detects some abnormality in cell. It usually acts in G1/S checkpoint (before the DNA replication starts in cell) and G2/M checkpoint (before the cell division begins). Hence, all of the above statements are true.
Codons that code for the same amino acid are termed synonyms, Silent mutations are base substitutions that result in no change of the amino acid or amino acid functionality when the altered messenger RNA (mRNA) is translated.
Answer:
cloning
Explanation:
one of the most controversial uses of genetic engineering has been cloning, or producing a genetically identical copy of organism. while the ethics of cloning are hotly debated, the 1st ever sheep was cloned in 1996 by scientists.
Sequential cleavage from the non-reducing terminals of glucose molecules is required for both glycogen degradation and polysaccharides hydrolysis.
Why non-reducing end is selected for digestion?
A polysaccharide's non-reducing end is the one where an anomeric carbon participates in the glycosidic connection. The elimination of carbohydrate remnants one at a time out from the non-reducing terminal occurs during glycogenolysis and polysaccharides hydrolysis.
- For example, several enzymes are involved in glycogenolysis in the liver and muscle.
- An example of such an enzyme is glycogen phosphorylase, which catalyzes the successive dissociation of the alpha 1->4 glycosidic bond that connects two glucose molecules at a non-reducing terminal of glycogen. The last glucose residue is eliminated as alpha-D-glucose 1-phosphate.
That is why non-reducing end of glucose is chosen for digestion or breakdown of the carbohydrate polymer.
Learn more about non-reducing here:
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Answer: B. Melting temperatures of primer should be between 55-80 degree Celsius.
Explanation:
Bacause the melting temperature controls the binding of the primers to your template DNA. At melting temperature 50% of the primer molecules are bound to their corresponding target sequence. If the difference in melting temperature between the two primers is too high, it might be difficult to find experimental conditions where both primers can bind to their target.
