Answer and Explanation:
The mechanism of action of statins begins with the inhibition of a protein called HMG-CoA reductase, allowing its substrate to accumulate in the body and promote cholesterol reduction. At that moment, a transporter called OATP (Organic Anion Transporting Polypeptides) takes statins to the epatic tissue where they will be transformed and metabolized until they are eliminated through bile. This elimination is influenced by the P-glycoprotein, which is the main cause of the efflix presented by the bili. This process can get help from other molecules like some protease inhibitors, digoxin and cyclosporine.
Answer:
A) A decrease in Na+ permeability, and an increase in K+ permeability.
Explanation:
When the potential action reaches a peak of about +40 mv Na+ channels are open and a high number of Na+ ions are entering the inside of the cell. Shortly after this happens the K+ channels will start to open their gates increasing the cell K+ permeability while the Na+ channels will start to close their gates, so the Na+ permeability will decrease. This happens in order to valance the positive charge on the inside of the cell. Normally the inside has a negative charge while the outside has a positive one, as the inside is more positive due to the increase in Na+ permeability at the beginning of the potential action, K+ cations (which are in abundance in the cell) will have to go out through the K+ channels so as to restore the charge valance, that means that there is an increase in K+ permeability.
Answer:
Isometric contraction
Explanation:
The length of the muscle is changed during contraction only when the muscle tension during contraction can outstand the resistance exerted by the object to be lifted.
During isometric contractions, the muscle tension is not sufficient to exceed the resistance of the object. Hence, there is no change in the length of the muscle. The isometric contraction does not bring about any body movements.
1: There are four stages of meiosis including prophase, metaphase, anaphase, and telophase. In the prophase phase (first stage) the chromosomes becomes visible as paired chromatids. When this happens the nuclear envelope disappears. During metaphase (second stage) the chromosomes attach to the spindle fibers. Throughout anaphase (third phase) the chromosomes move to opposite sides of the spindle fibers. While in telophase (fourth stage) two nuclei form by chromosomes and chromatids moving to the opposite ends of the cell.
2: The cells that outcome from meiosis are haploid daughter cells.
3: Haploid.
4: The similarities of meiosis and mitosis are that they both outcome with daughter from a parent cell. Differences are that mitosis has one round of genetic separation and cellular division while meiosis has two. In meiosis it creates daughter cells that aren’t identical.
Sexual reproduction combines genetics from two parents while asexual reproduction have offspring exactly the same as the genetics of the parent.
Asexual reproduction has the advantage of quicker reproducing. Sexual reproduction have all different offspring that can adapt to many different environments.
