The corpus callosum, a tight region of axons (whitematter), is the direct connection and thus communication between left and right hemispheres. A "split-brain" could result from disruption of or damage to the corpus callosum, either in part or whole.
The corpus callosum is a white-colored brain structure that connects the two hemispheres (right and left) of human brains. This connection established by the corpus callosum is extremely important, as the two hemispheres work together. It is due to the separation of the corpus callosum that we can see that the brain is divided into two hemispheres.
The corpus callosum is formed by several bundles of communication neural fibers (set of axons and dendrites). It is located in the central region of the human brain, where these beams pass from side to side.
The proteinaceous particles that lack nucleic acids and are not viruses are termed as prions.
In the healthy brain tissue, the prion proteins are present in the form PrPC, however, in case of prion disease, the normal protein becomes denatured and misfolded and exists in the rogue form which is PrPSc.
The normal form that is PrPC mainly exists in the form of alpha-helices and can bind to copper, however, the rogue form exists mainly in the beta-sheet configuration and is resistant to proteolysis.
