Hemoglobin is a protein in the blood that is made of 4 polypeptide chains. Two alpha chains are composed of 141 amino acids each
Two beta chains are 146 amino acids long. There a total of 574 amino acids in a hemoglobin molecule. People with sickle cell anemia have one incorrect amino acid in their beta chain. The first seven amino acids in the beta chain for hemoglobin A (normal) and hemoglobin S (sickle cell) are listed below. Which amino acid is different in hemoglobin S?
Amino acid differs at the glutamine, which is converted to valine in hemoglobin S. the body produced hemoglobin S due to a point mutation in the DNA sequence which results in different amino acid to be formed during translation of DNA sequence codons.
