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riadik2000 [5.3K]
3 years ago
15

Infantile Tay-Sachs is a fatal disease caused by a recessive allele passed from parents to offspring. Jennifer had a baby brothe

r who died of Infantile Tay-Sachs disease (TSD), but Jennifer did not have the disease. When she grew up and got married, her third child also died of Infantile TSD. How is this possible?
Biology
2 answers:
Lilit [14]3 years ago
8 0

Jennifer and her husband were both carriers of the allele

sveticcg [70]3 years ago
3 0
The father of Jennifers child was also carrying the recessive allele for TSD, if we label the dominant A and the recessive(disease allele) it becomes clear. Jennifer will be a heterozygous Aa, carrying the allele for the disease but as she is heterozygous the allele is not expressed. Likewise the father of her children is Aa. Thus there is a 25% chance of and offspring inheriting both recessive alleles from mother and father and thus expressing the disease. This is a prime example of how recessive traits can go many generations before expressing themselves.

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