Question

High-energy bonds between phosphate groups in nucleotide triphosphates (nucleotides in which three phosphate groups are attached to the 5′ carbon atom of the deoxyribose sugar). The enzyme uses this energy to catalyze the formation of a phosphodiester bond when incorporating new nucleotides into the growing chain. How does this information explain why DNA chains grow during replication in the 5′-to-3′ direction?

Answer 1

Answer:

Explanation:

The DNA is elongated in the 5'-to-3' end direction, meaning that the DNA polymerase adds a new nucleotide to the free 3' end OH- group. The DNA polymerase will catalyze formation of the bond between the 3' OH- group at the end with the 5' phosphate group of the new nucleotide forming the phosphodiester bond.