The establishment of "Tobacco as a major Cash Crop" is the right answer.
John Rolfe introduced Tobacco (a commercial crop) in the colony of Virginia in 1612. During the course of time, Tobacco became the basis of the Economy of Colonial Virginia. The cultivation of tobacco required a big labor force, hence, the colonists used to purchase the bound servants and slaves to cultivate it.
Improvements in technology definitely changed how people worked. Jobs in factories just became easier, for example, industrial lubrication helped machines run smoothly which made their job easier and the process faster.
It changed how people lived, too. Purchasing clothing and goods costed less because of the technology.
I believe the Indian Removal Act.
Isnt it where the battle of yorktown took place?