In the history of Europe, the Middle Ages (or medieval period) lasted from the 5th to the 15th century. It began with the fall of the Western Roman Empire and merged into the Renaissance and the Age of Discovery.
The "he" here is Constantine the Great, and he moved the capital of the Roman Empire to the city named Constantinopole, previously Byzantium, which today is known as Istanbul, Turkey's biggest city.
Answer:
Settlers were in a violent conflict with the Cayuses.
The Cayuses attacked the Whitman Mission in 1847.
The war is an example of what led to the creation of reservations.
Explanation: