The largest is the Biosphere
ANSWER: CANCER DEVELOPMENT
EXPLANATION:
Tumor suppressor genes (TSGs) are genes that regulates the cell cycle of a cell (i.e the cell division and replication). In other words, TSGs encodes protein that act as control or regulator of cell growth.
However, when there is an alteration in the genetic sequence (mutation) of the TSGs, this make the cell not to respond to cues that had been regulating it growth.
Thus, when cell growth is not regulated, it results to runaway or abnormal cell growth (i.e multiple folds cell division and replication), in other word referred to as “cancer”.
The pyloric sphincter is compose of smooth muscle and is located between the pylorus in the stomach and duodenum of the small intestine. In digestion, it serves as a valve controlling the flow of food thus it prevents the contents of small intestine backing up into the stomach.