Answer:
A. The chromatin near cis-regulatory sequences will be more closed and there will be less transcription.
Explanation:
In the presence of histones, the cis-regulatory sequences of DNA like promoter, enhancers etc. are not exposed. The function of the histone acetyltransferases (HATS) is to cause chromosome decondensation i.e. removal of histones from the DNA so that transcription of the DNA could occur. Histone acetyltransferases (HATS) cause acetylation of lysine amino acid of the histone proteins. Acetyl group is negatively charged so the acetylation of histone proteins leads to the removal of their positive charge which ultimately leads to the decrease in the interaction between N terminal of histones and negatively charged phosphate group of the DNA molecule. As soon as histones are removed from the DNA where cis-regulatory sequences are located, the DNA becomes accessible for transcription.
But here a drug has been added which blocks the activity of histone acetyltransferases (HATS) in cancer cells. So it is quite evident that in these cells, histones will not get removed from the cis-regulatory sequences of DNA so the DNA will be more closer or tightly packed as a result of which less transcription will occur.
Answer:
The period focused on self-actualization and one's ability to accept what is going on in one's life. The earliest Renaissance literature appeared in Italy in the 14th century; Petrarch, Machiavelli, and Ariosto are notable examples of Italian Renaissance writers.
Explanation:
Other population of the primary consumer or to what the consmers eat will expand in number
Answer:
Causal association is defined as two events in which one event leads to the cause/development of the second event such as the consumption of trans-fats and the onset of heart disease. In order to show the causal association, it is necessary to ensure that the 3 criteria of temporality, consistency, and strength are satisfied with respect to the relationship between consumption of trans fats and heart disease. According to this example involving the relationship between trans-fats and heart disease, temporality could be satisfied if one is consuming an excessive amount of foods containing trans-fats such asFrench fries, and who then ends up suffering from heart disease. In order to fulfill the criteria of strength, statistical tests would need to be performed in order to establish that there is a positive correlation between the individuals who consume trans-fats 10 times per week are shown to develop and require treatment for heart disease 90% of the time. Lastly, consistency may be fulfilled by showing that the same results are occurring despite applying the same testing measures on different groups of individuals during various increments. By applying the same tests on different groups, the chances of creating false-positives within the study can be significantly lowered. Numerous studies can be used to determine whether meaningful statements regarding the causal relationship between two factors can be established. By performing multiple studies on individuals’ eating habits and their health outcomes, researchers may then determine whether a relationship exists between the health challenges that they are faced with and the items that they consume.
Explanation:
