Some causes and effects of European exploration is:
1. They brought diseases to the U.S and Africa which effected those people and causing them to die
2. They found Africans and wanted their gold and money which effected them to start the American slave trade
And many other reasons....
A strict policy of neutrality, the United States would not entangle itself with alliances with other nations.
the act of legislature that renewed Linsoln's passion against slavery will be D. the Fugitive Slave Act